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  夏斌
职务:教育部“长江学者奖励计划”特聘教授 
北京核磁共振中心主任兼首席科学家
澳门游戏网站大全(中国)有限公司分析化学专业博士生导师
公司生命科学学院生物化学与分子生物学专业博士生导师
个人简历: 1989年毕业于公司生物系 获学士学位
  1997年在美国University of Wisconsin-Madison
获博士学位
  1997年至2001年在美国The Scripps Research Institute
博士后
     
联系方式: Tel: 010-62758127
Fax:010-62753790
E-mail: binxia@pku.edu.cn
 
     
研究兴趣: 蛋白质结构与功能关系的核磁共振谱学研究
蛋白质的结构基因组学研究
疾病的代谢组学研究
 


2005年以来主要代表文献:

  1. C-terminal domain of SARS-CoV main protease can form a 3D domain-swapped dimer. Zhong N, Zhang S, Xue F, Kang X, Zou P, Chen J, Liang C, Rao Z, Jin C, Lou Z, Xia B. Protein Sci. 2009 Apr;18(4):839-44. PMID: 19319935
  2. Automics: an integrated platform for NMR-based metabonomics spectral processing and data analysis. Wang T, Shao K, Chu Q, Ren Y, Mu Y, Qu L, He J, Jin C, Xia B. BMC Bioinformatics. 2009 Mar 16;10:83. PMID: 19291281
  3. A novel Bcl-XL inhibitor Z36 that induces autophagic cell death in Hela cells.
    Lin J, Zheng Z, Li Y, Yu W, Zhong W, Tian S, Zhao F, Ren X, Xiao J, Wang N, Liu S, Wang L, Sheng F, Chen Y, Jin C, Li S, Xia B. Autophagy. 2009 Apr;5(3):314-20. Epub 2009 Apr 16. PMID: 19242113
  4. Solution structure of human zeta-COP: direct evidences for structural similarity between COP I and clathrin-adaptor coats. Yu W, Lin J, Jin C, Xia B. J Mol Biol. 2009 Mar 6;386(4):903-12. PMID: 19167404
  5. Solution structure of GSP13 from Bacillus subtilis exhibits an S1 domain related to cold shock proteins. Yu W, Hu J, Yu B, Xia W, Jin C, Xia B. J Biomol NMR. 2009 Apr;43(4):255-9. PMID: 19152054
  6. Solution structure and catalytic mechanism of human protein histidine phosphatase 1. Gong W, Li Y, Cui G, Hu J, Fang H, Jin C, Xia B. Biochem J. 2009 Mar 1;418(2):337-44. PMID: 18991813
  7. Without its N-finger, the main protease of severe acute respiratory syndrome coronavirus can form a novel dimer through its C-terminal domain. Zhong N, Zhang S, Zou P, Chen J, Kang X, Li Z, Liang C, Jin C, Xia B. J Virol. 2008 May;82(9):4227-34. Epub 2008 Feb 27. PMID: 18305043
  8. 1H, 13C, and 15N resonance assignments of human ζ-COP. Wenyu Yu, Changwen Jin and Bin Xia (2008) Biomolecular NMR Assignments 2008 2:73–75.
  9. 1H, 13C, and 15N resonance assignments of a general stress protein GSP13 from Bacillus subtilis. Wenyu Yu, Bingke Yu, Jicheng Hu, Wei Xia, Changwen Jin, Bin Xia (2008) Biomolecular NMR Assignments 2008 2:163–165
  10. 1H, 13C, and 15N resonance assignments of human phosphohistidine phosphatase 1 (PHPT1)Weibin , Gaofeng Cui, Changwen Jin and Bin Xia Biomolecular NMR Assignments 2007 1:229-231
  11. Gossypol induces Bax/Bak-independent activation of apoptosis and cytochrome c release via a conformational change in Bcl-2. Lei X, Chen Y, Du G, Yu W, Wang X, Qu H, Xia B, He H, Mao J, Zong W, Liao X, Mehrpour M, Hao X, Chen Q. FASEB J. 2006 Oct;20(12):2147-9. Epub 2006 Aug 25. PMID: 16935937
  12. Structural insight into poplar glutaredoxin C1 with a bridging iron-sulfur cluster at the active site. Feng Y, Zhong N, Rouhier N, Hase T, Kusunoki M, Jacquot JP, Jin C, Xia B. Biochemistry. 2006 Jul 4;45(26):7998-8008. PMID: 16800625
  13. Identification and solution structures of a single domain biotin/lipoyl attachment protein from Bacillus subtilis. Cui G, Nan B, Hu J, Wang Y, Jin C, Xia B. J Biol Chem. 2006 Jul 21;281(29):20598-607. Epub 2006 May 14. PMID: 16699181
  14. Periplasmic protein HdeA exhibits chaperone-like activity exclusively within stomach pH range by transforming into disordered conformation. Hong W, Jiao W, Hu J, Zhang J, Liu C, Fu X, Shen D, Xia B, Chang Z. J Biol Chem. 2005 Jul 22;280(29):27029-34. Epub 2005 May 23. PMID: 15911614
  15. 1H, 15N, and 13C resonance assignments of reduced glutaredoxin C1 from Populus tremula x tremuloides. Feng Y, Rouhier N, Jacquot JP, Xia B. J Biomol NMR. 2005 Mar;31(3):263-4. No abstract available. PMID: 15803403
  16. 1H, 13C, and 15N resonance assignments of the N-terminal domain of the SARS CoV nucleocapsid protein. Zhong N, Huang Q, Jin C, Xia B. J Biomol NMR. 2005 Jan;31(1):79-80. No abstract available. PMID: 15692748
     
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